Aoi Uzuki is the mother of Shion and Jin Uzuki, and the wife of Suou Uzuki. She originally came from the Vassilios system, which was largely populated by people from the Immigrant Fleet. Because of this, Aoi and her children possess certain latent traits associated with those from the Immigrant Fleet. Unfortunately, those traits caused Aoi to slip into a coma which she never recovered from. It is later discovered in Episode III that Shion is suffering from the same disease as her mother. Aoi was then taken to the Mizrahi Cerebral Sciences Acute Neurosies Treatment Facillity, a place also known as Labyrinthos. Her husband Suou Uzuki, head of the Federation Special Inspection Office of Advanced Technology Department of Energy, performed experiments on her unconscious mind at Labyrinthos while working with Joachim Mizrahi to try and align the Vessels of Anima for use by humans in E.S. craft. Her data was stored in Mizrahi's database onboard the Proto Merkabah and can be seen in Episode I, when Shion and the party are aboard it. Her name incorrectly comes up as "Vwud Uzuki" for some reason.
Aoi Uzuki was murdered during the Miltian Conflict, by being stabbed repeatedly by three 27-Series Asuras while she was unconscious. Shion witnessed this traumatic event, and afterwards, began to experience hallucinations, believing that she could restore her parents' lives if she were to put all of their spilled blood back into their bodies.