DME Addiction is a physical and mental illness caused by the consumption of Realian flesh. Realian skin and neurological (brain) tissue is extremely addictive, almost like a drug. Furthermore, like a drug, the Realian skin and neuro tissue causes physical mutation and complete emotional addiction, primarily due to the tissue chemical being absorbed into the bloodstream, while the small, solid particles collect around the veins. Lieutenant Virgil had a severe case of DME Addiction. His skin was completely hardened, and a majority of his veins were clearly visible as long bumps on the surface. This is one of many examples of obvious Realian mistreatment.