In T.C. 4591, the Draper region of Abraxas was opened up to private use by Dmitri Yuriev after a branch of the Yuriev Institute was built there. Every private business in the biotechnology sector set up shop in the area, hoping to enjoy the new benefits provided by the Life Recycling Act in a region closely linked with Yuriev.
The Yuriev Institute seen in Episode II was established in the 4660s.
Rubedo, Albedo, and Nigredo were kept at the institute, not allowed to leave. While there, the three frequently traveled into Sakura Mizrahi's mind via the Encephalon. These Encephalon tests were often extremely tedious; they often took a severe toll on the U.R.T.V. units. The Yuriev Institute was very much like a school for the gifted; many U.R.T.V. children would show off their sometimes gruesome talents such Albedo's regenerative power shown many times in Episodes I and II.
After the Miltian Conflict, only four U.R.T.V.s survived: the variants. Since then, the Yuriev Institute halted development of any more U.R.T.V.s.
After the Miltian Conflict Edit
Xenosaga I&II reveals that Yuriev Industries is being maintained by a group called the Salvator Faction in Dr. Yuriev's "absence." Its infrastructure is still operational; all of Yuriev's inner circle had been waiting for was Dr. Yuriev's reawakening in the body of his "son," Nigredo (aka Gaignun Kukai).
In Episode III, Yuriev returns to the head of his corporation, quickly using the Salvator Faction to gain considerable sway in the Federation Parliament. Under his orders, the company quickly sets to work on two new weapons based on the designs of Joachim Mizrahi, Ω Res Novae and the Tactical Warship Merkabah.